|
|
cancer alternative therapy hyperthermia tumor holistic medicine biologic immune system immunotherapy less toxic chemotherapy breast treatment cervical, inflamatory breast cancer, sarcoma lung lymphoma metastases ovarian prostate skin thyroid tonsil throat stomach colon glioblastoma melanoma soft tissue sarcoma mouth neck metastatic natural no side effects non-invasive oncology research consultation advice center failure cytotoxic agents effects cytotoxicity drug resistance effect p53 p16 RAS p21CIP1/WAF1 p27KIP1 p57KIP2 E2F bcl-2 BAX Promoter Gene growth arrest DNA damage protein apoptosis induction suppressor gene genetic alteration advanced disease metastatic microcirculation blood flow modification neoplasm analysis whole body hyperthemia vegetarianism wholebody local carcinoma succes anthracyclines vinca alkaloids epipodophylline derivatives cisplatin carboplatin mitomycin paclitaxel ACNU BCNU hyperglycemia transmembrane verapamil localized expression p170 wild-type p53 function MDR 1 expression classic p170 positive MDR atypic P170 negative MDR non-multi-drug-resistance non-MDR Mechanism Glutathione-S-Transferase GST Glutathionperoxidase Poly(Adenosindiphosphate (ADP)-Ribose) Polymerase PARP Proteinkinase C PKC Topoisomerase Glutathion GS Humane Metallothioneine relapse
Successful therapy for human cancers is apparently limited by intrinsic or acquired multidrug resistance (MDR) toward cytostatic drugs... The following effects of hyperthermia could play a very important role in overcoming MDR ... Apoptosis plays a variable role in the response of tumors to mild
hyperthermia... Many biological attributes of tumors can deteriorate homogeneity distribution of heat during hyperthermia... There is a direct correlation
between the deterioration of the microcirculation in tumor tissue and itīs alteration throughout the thermoradiochemotherapy... Possibilities of modification of hyperthermia in the complex treatment of
malignant neoplasmas... Experience of hyperthermia efficacy in the threatment of advanced therapy resistant tumors... Whole Body Hyperthermia combined
with chemotherapy in patients with chemotherapy resistant ovarian cancer, breast cancer... Alternative, biologic support for cancer treatment. Essential unity of mind, body and spirit - holistic model in medicine...
Consultations, counseling service, advice center, deliberation and individual program... Medical information see also by Journals of The National Cancer Institute, Full Coverage Cancer Research, Association of Cancer Online Resources, Imperial Cancer
Research Fund and more...
